Abstract Background There is little existing knowledge about actual quality of drugs provided by different providers in Nigeria and in many sub-Saharan African countries.Such information is important for improving malaria treatment that will help in the development and implementation of actions designed to improve the quality of treatment.The objec
Amazonia. Violencias, resistencias, propuestas
The Amazon, that huge South American territory which accommodates two main dichotomies, abundance and violence, is permanently struggling between life and death.For a long time the immense Amazon rainforest was seen as a reserve of natural resources where the capital would go shopping as it pleased.The very complexity of this territory requires new
A Comprehensive Review on Source, Types, Effects, Nanotechnology, Detection, and Therapeutic Management of Reactive Carbonyl Species Associated with Various Chronic Diseases
Continuous oxidation of carbohydrates, lipids, and amino acids generate extremely reactive carbonyl species (RCS).Human body comprises some important RCS namely hexanal, acrolein, 4-hydroxy-2-nonenal, methylglyoxal, malondialdehyde, isolevuglandins, and 4-oxo-2- nonenal etc.These RCS damage important cellular components including proteins, nucleic
Application of Immune Checkpoint Inhibitors in the Treatment of Cholangiocarcinoma
Cholangiocarcinoma is a general term for intrahepatic and extrahepatic malignant tumors deriving SHOPSTORM_HIDDEN_PRODUCT in the biliary system.According to the location, it is divided into intrahepatic cholangiocarcinoma, hilar cholangiocarcinoma, and distal cholangiocarcinoma.Progressive cholangiocarcinoma yields poor outcomes with radiotherapy;
Improvement in reliability quantification to support BS EN 61511 failure probability analysis
Estimation of failure rates provides a key input to quantitative risk assessment (QRA) quantification.International functional safety standard such as BS EN 61511 specifies use of realistic and credible failure data in failure probability analysis.In traditional reliability assessment, mean time to failure is one of the most common approaches to fi